Midwest Fetal Care Center: Research and outcomes

Midwest Fetal Care Center: Research and outcomes


At the Midwest Fetal Care Center, our team is committed to improving outcomes for moms and babies facing high-risk pregnancies. Research – combined with our high volume experience, teaching and the identification and utilization of evidence-based practices – is a large factor in that success. 

The Midwest Fetal Care Center is part of the North American Fetal Therapy Network (NAFTNet), an association of medical centers with proven expertise in fetal surgery and other fetal services. Our fetal specialists are active in national fetal therapy associations and have been published in peer-reviewed medical journals. Members of our multidisciplinary care team regularly generate national research abstracts related to the clinical protocols/algorithms that we create.

Through Institutional Review Board (IRB) funding, we are advancing research and knowledge in the following areas related to our top diagnoses:

Tracking Outcomes

Critical to measuring the impact of early fetal intervention is the ability to measure the short and long term clinical outcomes of mothers and their babies. Within the existing network of advanced fetal centers, the REDCap Database is the primary internet-based, HIPAA-compliant tool that facilitates consistent data tracking and outcomes measures, with capabilities to produce custom and standard reports.  The Midwest Fetal Care Center tracks clinical information using REDCap.

Other Outcomes

  • Targeted data collection for top diagnoses
    - CDH, TTTS, gastroschisis, single ventricle and congenital lung lesions
  • Measuring prenatal markers to risk stratify our patients
    - CCAM volume ratio (CVR)
    - Lung to head ratio (LHR)
    - Tumor Volume ratio (TVR)
    - Omphalocele ratio 

International Laser Ablation Results

 NAt Least
Single Survivor* (%)
Eurofetus (2004, NEJM)727657
Crombleholme (2007, Am J Ob Gyn)206591
Chmait (2010, J Mat Fet Neo Med)999172
Morris (2010, BJOG)1648562

*Note: MWFCC always defines survivors as infants discharged to home. Perinatal survival is defined as the percentage of fetuses that survive to discharge after undergoing laser ablation surgery. Results as of July 2013.


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